MicroActive® Resveratrol

Antioxidant Polyphenol

Resveratrol is an antioxidant polyphenol with great promise for supporting healthy metabolism, normal insulin sensitivity, and optimal blood flow — all of which may have cardiovascular, brain, and healthy aging benefits.*

However, resveratrol, while reasonably well-absorbed, has a very short half-life. Because it does not stay in the bloodstream very long, its benefits can be difficult to reap. After oral administration, the amount of free resveratrol in plasma accounts for less than 2% of total resveratrol. In some instances, it isn’t even detected.

Microactive Resveratrol Benefits:

MicroActive® Resveratrol was developed to address this issue through a micronized, sustained-release technology that allows for better absorption and retention.

MicroActive® Resveratrol is superior to standard resveratrol because it offers:

12-hours sustained release
Increased systemic exposure
Effective at low doses
2.5x more bioavailability than standard resveratrol

Microactive Resveratrol Benefits Proven in Research

MicroActive® Resveratrol was compared with 99% resveratrol powder in a dissolution study that approximated transport through both the gastric and intestinal environments. Compared with resveratrol powder, MicroActive® Resveratrol dissolved slowly and demonstrated sustained release over a longer period. The resveratrol powder showed complete dissolution (100%) in 4 hours. The MicroActive® formula showed sustained release over 12 hours, with 97% of the dose released.

In a pilot study, resveratrol powder showed a rapid absorption with a sharp peak at Tmax of 2 hours postdose. After 2 hours, the plasma levels of total resveratrol declined rapidly with a small increase at 9 hours. MicroActive® resveratol also showed a Tmax at 2 hours and lower Cmax (max. concentration at Tmax) with a broader peak and higher plasma levels compared with the control. Sustained release continued for > 9 hours. This implies that while 98% resveratrol powder is rapidly absorbed and excreted, MicroActive® resveratrol continues to remain in circulation for a long time.

MicroActive® Resveratrol Product Specifications:

30% Resveratrol concentration
Resveratrol in a sustained-release matrix
Off-white powder
Shelf life of 4 years
Suitable for capsules, powders, tablets, liquids (water dispersible), softgel capsules